Synergistic Effect of Polydatin and Polygonatum sibiricum Polysaccharides in Combating Atherosclerosis via Suppressing TLR4-Mediated NF-κB Activation in ApoE-Deficient Mice

Figure 5

Effect of the combination of PD and PSP on protein expression of TLR4, MyD88, p-p65, and p65 in aorta of HFD-induced atherosclerosis ApoE–/– mice: (a) TLR4, MyD88, p-p65, p65, and GAPDH expression exposed in WT group, model group, PD + PSP group, PD + PSP + TAK-242 group, TAK-242 group; (b) statistical chart of TLR4; (c) statistical chart of p-p65/p65; (d) statistical chart of MyD88. Data are presented as the mean ± standard deviation (n = 3). ^a, compared to the WT group; ^b, compared to the model group; ^c and ^d, compared to the TAK-242 group; ^e and ^f, compared to the PD + PSP group.

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