FAM117A Is a New Prognostic Marker of Lung Adenocarcinoma and Predicts Sensitivity to PD0332991

Figure 1

FAM117A expression is decreased in lung cancer patients. (a) Kaplan–Meier overall survival curve comparing the high (50%–100%, N = 267) and low (0%–50%, N = 268) expression value of FAM117A (determined by the quantile value) for the TCGA LUAD patient cohort. (b) Kaplan–Meier overall survival curve comparing the high (50%–100%, N = 134) and low (0%–50%, N = 135) expression value of FAM117A (determined by the quantile value) for the TCGA LUAD patient cohort. (c) Dot plot of the FAM117A mRNA expression between lung cancer tissue (N = 535) and adjacent normal tissue (N = 59). (d) Dot plot of the FAM117A mRNA expression between paired lung cancer tissue (N = 59) and adjacent normal tissue (N = 59). (e) Dot plot of the FAM117A protein expression between lung cancer tissue (N = 111) and adjacent normal tissue (N = 102). (f) Dot plot of the FAM117A mRNA expression between paired lung cancer tissue (N = 102) and adjacent normal tissue (N = 102). (g) Box plot of FAM117A expression among patients of different T stages (T1: N = 175; T2: N = 289; T3: N = 49; T4: N = 19). (h) Box plot of FAM117A expression among patients of different N stages (Normal: N = 59; N0: N = 348; N1: N = 95; N2: N = 74).

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