FAM117A Is a New Prognostic Marker of Lung Adenocarcinoma and Predicts Sensitivity to PD0332991

Figure 2

Identification of differentially upregulated expressed genes. (a) Volcano plot of mRNA expression changes between LUAD samples harboring FAM117A high- and low- expression value. The X-axis specifies the fold-change (FC) and the Y-axis specifies the negative logarithm to the base 10 of the adjusted p values. (b) Heatmap of differentially expressed genes between LUAD samples harboring FAM117A high- and low-expression values. (c, d) KEGG Gene Ontology enrichment analysis for upregulated (c) and downregulated (d) genes, respectively. (e, f) KEGG enrichment analysis for upregulated (E) and downregulated (f) genes, respectively. (g, i) Gene set enrichment analysis between FAM117A high- and low-expression lung cancer samples. (j, k) Protein-protein interaction network and MCODE components identified in upregulated genes with low FAM117A expression.

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