FAM117A Is a New Prognostic Marker of Lung Adenocarcinoma and Predicts Sensitivity to PD0332991

Figure 5

PD0332991 rescued the accelerated cell growth induced by FAM117A knockdown. (a) Representative images of the cell cycle profile determined by flow cell cytometry in lung cancer cells transfected with negative control oligo or shRNA oligos targeting the FAM117A transcript or combined treated with PD0332991. (b) Quantitative analysis results of cell cycle analysis. (c, d) Representative images of EDU labelling lung cancer cells (NCI-H1975 and A549 treated with PD0332991 at 100 nM or DMSO) captured by immunofluorescence microscope. (d) Quantitative analysis results.(e, f) Images of colony formation and quantitative results for lung cancer cells (NCI-H1975 and A549 treated with PD0332991 at 100 nM.

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