Buyang Huanwu Decoction: A Traditional Chinese Medicine, Promotes Lactate-Induced Angiogenesis in Experimental Intracerebral Hemorrhage

Figure 3

Representative images of (a) HIF-1α and (b) VEGF immunoreactivities on day 7 were shown. Barely any HIF-1α (a) and VEGF (b) immunoreactivity was found in the Sham group, and many HIF-1α⁺ (a) and VEGF⁺ (b) microvessels were detected around the hematoma after ICH in the enlarged profile. Immunofluorescence double labeling confirmed that (c) HIF-1α and (d) VEGF were localized to vWF-positive vessels. Scale bar = 100 μm (a, b). Scale bar = 50 μm (c, d).