|
| Study (country) | Year | Study design | Total participants, n (male/female) | Intervention group (I), n (age, years); control group (C), n (age, years) | Characteristics | Comparison | Outcome measurements |
|
| Stefanelli et al. [16] (Italy) | 2013 | RCT | 40 (23/17) | I: 20 (<75)
C: 20 (75)
65 ± 7 | NSCLC (stage I/II) and COPD; open thoracotomy | Usual care (preoperative preparation) | CPET
PFT |
| Zhang and Zhao [17] (United States) | 2011 | RCT | 19 (9/10) | I: 10 (70.2 ± 8.61)
C: 9 (72.0 ± 6.69) | Lung cancer and COPD; open thoracotomy or VATS | Usual care (preoperative preparation) | PPCs
LOS
Adverse effects |
| Zhang et al. [18] (China) | 2014 | RCT | 86 (56/30) | I: 43 (64.98 ± 2.7)
C: 43 (64.53 ± 2.62) | NSCLC (stages I–III) and COPD; open thoracotomy or VATS | Usual care (preoperative preparation) | PPCs
LOS
6MWD |
| Lai et al. [19] (China) | 2016 | RCT | 48 (28/20) | I: 24 (63.13 ± 6.26)
C: 24 (64.04 ± 8.94) | NSCLC (stages I–IV) and COPD; open thoracotomy or VATS | Usual care (preoperative preparation) | PPCs
LOS
6MWD
Health-related quality |
| He [20] (China) | 2018 | RCT | 110 (72/38) | I: 55 (68.5 ± 5.6)
C: 55 (69.3 ± 6.1) | NSCLC and COPD; open thoracotomy or VATS | Usual care (preoperative preparation) | PPCs
LOS
CPET
PFT |
| Saito et al. [6] (Japan) | 2017 | CT | 62 (54/8) | I: 31 (72.0 ± 8.8)
C: 31 (71.3 ± 6.5) | NSCLC (stages I–II) and COPD; open thoracotomy or VATS | Usual care (preoperative preparation) | PPCs
PFT
LOS |
| Mujovic et al. [21] (Serbia) | 2015 | CT | 103 (90/13) | I: 56 (72.0 ± 8.8)
C: 47 (71.3 ± 6.5) | NSCLC and COPD; open thoracotomy or VATS | Usual care (preoperative preparation) | LOS
PFT
6MWD |
| Sekine et al. [22] (Japan) | 2005 | CT | 82 (76/6) | I: 22 (70.4 ± 4.6)
C: 60 (69.0 ± 5.5) | NSCLC (stages I–IV) and COPD;
Lobectomy | Usual care (preoperative preparation) | PPCs
LOS
PFT |
| Meng et al. [15] (China) | 2018 | CT | 101 (63/38) | I: 43 (58.9 ± 8.9)
C: 58 (61.1 ± 9.1) | NSCLC (stages I–III) and COPD; VATS | Usual care (preoperative preparation) | PPCs
LOS
PFT |
|
