Evaluation of the Antiulcer Activity of Methanolic Extract and Solvent Fractions of the Leaves of Calpurnia aurea (Ait.) Benth. (Fabaceae) in Rats

Table 2

The impact of Calpurnia aurea crude extract on ulcer index, gastric volume, total acidity, pH, and stomach mucin level in pyloric-ligated rats.

Group	Ulcer index	%UI	Gastric volume (mL)	pH	Acidity in mEq/L	Mucus content (μg/g)
NC	17.75 ± 1.82	—	2.97 ± 0.46	2.08 ± 0.05	51.65 ± 1.42	61.64 ± 1.05
CALE100	17.17 ± 1.39	3.3	2.83 ± 0.44	2.32 ± 0.08	50.16 ± 2.15	63.84 ± 1.31
CALE200	11.17 ± 2.39e	37.1	2.80 ± 0.24	2.73 ± 0.20e	47.53 ± 0.76e	67.46 ± 1.00e
CALE400	8.17 ± 2.60e	54	1.32 ± 0.10e	4.73 ± 0.05e	32.81 ± 0.45e	74.77 ± 1.53e
OM20	7.92 ± 2.51e	55.4	1.28 ± 0.10e	4.88 ± 0.09e	31.27 ± 0.61e	78.50 ± 1.10e

Values are expressed as mean ± SEM (n = 6) and analyzed using one-way ANOVA, followed by Tukey’s post hoc test. ^eCompared with negative control. , , and . NC = negative control, CALE = Calpurnia aurea leaf extract, OM20 = omeprazole 20 mg/kg, %UI = percent ulcer inhibition, mL = milliliter, mEq/L = milliequivalents per liter, and μg/g = microgram per gram.