Evaluation of the Antiulcer Activity of Methanolic Extract and Solvent Fractions of the Leaves of Calpurnia aurea (Ait.) Benth. (Fabaceae) in Rats

Table 3

The effect of Calpurnia aurea crude extract on ulcer number, ulcer score, and ulcer index in acidified ethanol-induced ulcer rats.

Group	Mean ulcer number (UN)	Mean ulcer score (US)	Mean ulcer index (UI)	%UI
NC	29.83 ± 1.25	49.00 ± 1.17	17.88 ± 0.23	—
CALE100	26.83 ± 1.78	42.10 ± 3.78	16.87 ± 0.56	5.6
CALE200	12.83 ± 1.17	16.75 ± 1.86	12.96 ± 0.30e	27.5
CALE400	1.50 ± 0.22	1.67 ± 0.69	10.32 ± 0.09e	42.3
SUC100	1.33 ± 0.21	0.83 ± 0.17	9.87 ± 0.04e	44.8

Values are expressed as mean ± SEM (n = 6) and analyzed using one-way ANOVA followed by Tukey’s post hoc test. ^eCompared with negative control. , and . NC = negative control, CALE = Calpurnia aurea leaf extract, SUC100 = sucralfate 100 mg/kg, UN = ulcer number, US = ulcer score, UI = ulcer index, and %UI = percent ulcer inhibition.