Evaluation of the Antiulcer Activity of Methanolic Extract and Solvent Fractions of the Leaves of Calpurnia aurea (Ait.) Benth. (Fabaceae) in Rats

Table 4

The ulcer-healing effect of Calpurnia aurea crude extract on ulcer number, ulcer score, and ulcer index in acetic acid-induced ulcer rats.

Group	Mean ulcer number (UN)	Mean ulcer score (US)	Mean ulcer index (UI)	%UI
NC	36.17 ± 0.87	64.92 ± 1.98	20.11 ± 1.69	—
CALE100	35.67 ± 0.67	55.58 ± 1.58	19.13 ± 1.69	4.9%
CALE200	5.67 ± 0.92	10.50 ± 1.76	11.62 ± 1.69e	42.2%
CALE400	4.00 ± 0.93	6.00 ± 1.49	9.33 ± 1.69e	53.6%
CM100	3.67 ± 0.88	5.25 ± 1.56	9.22 ± 1.69e	54.2%

Values are expressed as mean ± SEM (n = 6) and analyzed using one-way ANOVA followed by Tukey’s post hoc test. ^eCompared with negative control. . NC = negative control, CALE = Calpurnia aurea leaf extract, CM100 = cimetidine 100 mg/kg, UN = ulcer number, US = ulcer score, UI = ulcer index, and %UI = percent ulcer inhibition.