Research Article
Aberrant Expression TFR1/CD71 in Gastric Cancer Identifies a Novel Potential Prognostic Marker and Therapeutic Target
Table 2
Correlation of TFR1 expression and clinicopathological characteristics.
| Variables | TFR1 expression | Total | X2 | value | Positive | Negative |
| Age (y) | | | | | | | ≥60 | 67 | 25 | 92 | 10.146 | | <60 | 30 | 33 | 63 |
| Gender | | | | | | | Male | 74 | 39 | 113 | 1.907 | 0.167 | Female | 23 | 20 | 43 |
| Location | | | | | | | Proximal | 35 | 13 | 48 | 4.413 | 0.110 | Distal | 54 | 42 | 96 | Total | 8 | 3 | 11 |
| Lauren type | | | | | | | Intestinal type | 55 | 19 | 74 | 11.821 | | Diffuse type | 28 | 27 | 55 | Mixed type | 14 | 10 | 24 | Unknown | 0 | 2 | 2 |
| Borrmann type | | | | | | | I + II | 50 | 39 | 89 | 4.118 | 0.128 | III + IV | 46 | 18 | 64 | Unknown | 1 | 1 | 2 |
| Differentiated degree | | | | | | | Well/moderate | 21 | 6 | 27 | 3.225 | 0.073 | Moderate-poor/poor | 76 | 52 | 128 |
| T stage | | | | | | | T1+2 | 1 | 7 | 8 | 9.035 | | T3+4 | 96 | 51 | 147 |
| N stage | | | | | | | N0+N1 | 23 | 19 | 42 | 1.504 | 0.220 | N2+N3 | 74 | 39 | 113 |
| M stage | | | | | | | M0 | 86 | 54 | 140 | 0.820 | 0.365 | M1 | 11 | 4 | 15 |
| TNM stage | | | | | | | I + II | 9 | 11 | 20 | 3.031 | 0.082 | III + IV | 88 | 47 | 135 |
| HER2 | | | | | | | Positive | 17 | 1 | 18 | 8.830 | | Negative | 80 | 57 | 137 |
| PD-L1 | | | | | | | Positive | 46 | 8 | 54 | 18.083 | | Negative | 51 | 50 | 101 |
| CEA | | | | | | | Positive | 30 | 10 | 40 | 3.551 | 0.060 | Negative | 67 | 48 | 115 |
| CA125 | | | | | | | Positive | 10 | 3 | 13 | 0.668 | 0.414 | Negative | 87 | 55 | 142 |
| CA72-4 | | | | | | | Positive | 24 | 6 | 30 | 4.820 | | Negative | 73 | 52 | 125 |
| AFP | | | | | | | Positive | 8 | 0 | 8 | 3.500 | 0.061 | Negative | 89 | 58 | 147 |
| CA19-9 | | | | | | | Positive | 35 | 16 | 51 | 1.187 | 0.276 | Negative | 62 | 42 | 104 |
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