Particulate Matter Exposure and the Changes in Immune Biomarkers: Effects of Biyeom-Go on the Nasal Mucosa of Patients with Allergic Rhinitis and a Particulate Matter-Treated Mouse Model

Figure 3

Effects of BYG and Nasonex treatment on expression of goblet cells and inflammatory factors in KDP20-induced mice. (a) Generation of a KDP-induced animal model and drug administration. (b) Representative images of goblet cells with PAS staining of nasal tissues in KDP20-treated mice. PAS-positive cells were distributed in the nasal epithelium. (c–g) mRNA expression of immune biomarkers. NOR, negative control; KDP20, Korea diesel particulate matter; BYG, Biyeom-go; Nasonex, positive control; PAS, periodic acid-Schiff; IL-33, interleukin 33; TSLP, thymic stromal lymphopoietin; TNF-α, tumor necrosis factor-alpha.