Tetramethylpyrazine and Paeoniflorin Synergistically Attenuate Cholesterol Efflux in Macrophage Cells via Enhancing ABCA1 and ABCG1 Expression

Figure 3

Tetramethylpyrazine-paeoniflorin pair increased cholesterol efflux mediated by ABCA1 and ABCG1 in foam cells. ((a)-(d)) The impact of tetramethylpyrazine and/or paeoniflorin on the relative protein intensity of cholesterol transporters in foam cells. ((e)-(g)) The relative mRNA intensity of cholesterol transporters in foam cells treated with tetramethylpyrazine and/or paeoniflorin. All data were shown as MD ± SEM of three independent experiments. (n = 3, vs. control, vs. control; vs. ox-LDL, vs. ox-LDL).

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