Research Article

Exploration on the Improvement of Cognitive Function and Inflammatory Response in Perimenopausal Patients with Mild Cognitive Impairment by Self-Prepared Ningshen Prescription

Table 1

Comparison of general data between the two groups.

DataControl group (n = 40)Therapy group (n = 40)t or χ2 value value

Age distribution (n, %)40∼45 years9 (22.50)7 (17.50)0.8250.843
46∼50 years14 (35.00)12 (30.00)
51∼55 years13 (32.50)16 (40.00)
56∼60 years4 (10.00)5 (12.50)
Age at menarche (years,  ± s)15.12 ± 1.3714.89 ± 1.430.7350.465
Duration of disease (months,  ± s)4.03 ± 0.914.06 ± 0.930.1460.884
Menopause (n, %)9 (22.50)7 (17.50)0.3130.576
Level of education (n, %)Illiterate4 (10.00)6 (15.00)1.3760.711
Primary school13 (32.50)12 (30.00)
Lower secondary16 (40.00)18 (45.00)
High school and above7 (17.50)4 (10.00)
Personal history (n, %)Smoking9 (22.50)11 (27.50)0.2670.606
Alcohol consumption7 (17.50)10 (25.00)0.6720.412
MocA (points,  ± s)21.32 ± 1.3421.51 ± 1.430.6130.542
ADL (points,  ± s)45.51 ± 8.2746.27 ± 7.870.4210.675
TCM symptom score (points,  ± s)16.23 ± 4.1016.57 ± 4.230.3650.716
hs-CRP (μmol/L,  ± s)15.87 ± 2.6315.42 ± 2.660.7610.449
Hcy (μmol/L,  ± s)14.21 ± 4.6914.87 ± 4.760.6250.534
IL-1β (ng/L,  ± s)50.22 ± 13.1850.46 ± 12.690.0830.934
ALT (U/L,  ± s)24.23 ± 4.0723.95 ± 3.890.3150.754
AST (U/L,  ± s)19.08 ± 3.7219.14 ± 4.030.0690.945
Cr (μmol/L,  ± s)80.24 ± 13.1581.07 ± 13.990.2730.785