Improvement in the Blood Urea Nitrogen and Serum Creatinine Using New Cultivation of Cordyceps militaris

Figure 4

Renal glomerular cross-sectional areas in the sham and uremic mice with or without C. militaris mycelia treatment. Four groups of partial nephrectomy ICR mice (weighing approximately 30 g) received a daily administration of media-treated C. militaris mycelia water solution (3 mg dried mycelia dissolved in 0.3 mL water) from culture in HKS, HKS + A, CM, or CM + A medium by oral gavage for 30 days, whereas the sham and Nx control groups received distilled water. The uremic groups showed significant hypertrophy of the remnant glomeruli compared with the sham group. Values are expressed as mean ± standard error of the mean.