Research Article
[Retracted] MiR-199 Aggravates Doxorubicin-Induced Cardiotoxicity by Targeting TAF9b
Figure 1
Cardiomyocytes (AC16 cells) was injured by DOX. (a) The cell proliferation rate in the DOX induction group was distinctly lower than that in the control group. (b) The levels of TNF-α, IL-1β, and IL-6 in the DOX induction group were obviously higher. (c) The LDH and MDA in the DOX induction group was higher than that in the control group, while SOD in the DOX induction group decreased relatively to the control group. (d) Cell apoptosis detection by flow cytometry. (e) Detection of apoptosis cells by TUNEL staining. (f-g) Apoptosis-related protein expression detection by qPCR. (h) Beclin-1 and LC3B expression detection by western blotting. , , and .
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