Toxicological Evaluation and In Silico Identification of Acetylcholinesterase Inhibitors in a Commercial Polyherbal Formulation (KWAPF01)

Figure 4

BOILED-Egg diagram of KWAPF01 secondary metabolites. BBB: blood-brain barrier permeant; HIA: passive human gastrointestinal absorption; PGP+: P-glycoprotein substrate; PGP−: non-P-glycoprotein substrate; Cry, cryptolepine; Met, 11-methoxy-10H-quindoline; Ter, terminalin-A; Ber, berberine; Nic, nicotine; Cat, catechol; Chr, chrysin; Api, apigenin; Gal, galangin; Arj, arjungenin; Don, donepezil; Fri, friedelin.