Research Article
The Antitumor Effect of TPD52L2 Silencing on Oxaliplatin-Resistant Gastric Carcinoma Is Related to Endoplasmic Reticulum Stress In Vitro
Figure 3
Effect of silencing of TPD52L2 on the viability of cells and colony-forming ability in gastric carcinoma cell lines (OXA resistant). (a, b) Viability of SGC-7901-OXA and MGC-803-OXA cells transfected with siCon or TPD52L2 siRNA-2 (siTPD52L2) was evaluated via MTT assay after culture for two days with increasing concentrations of OXA. IC50 (μM) values of cells were measured. (c) Illustrative images of cloning-forming assays. (d) Stained colonies (>1 mm in diameter) were counted. All values are indicated as mean ± SD of three replicates. value <0.05 and value <0.01 compared to the siCon group.
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