Review Article

Efficacy and Safety of Electroacupuncture for Pain Control in Herpes Zoster: A Systematic Review and Meta-Analysis

Table 1

Characteristics of included studies.

StudyPublish yearSampleInterventionAge (years)Sex (M/F)Disease course (days)Outcome measure
CECECECECC

Song [21]20093030RT: Valaciclovir, 300 mg, orally three times daily for ten days; vitamin B1, 10 mg, orally three times daily for ten daysEA: EA on the Jiaji (EX-B2) + Zhigou (TE6) + Houxi (SI 3); sparse and dense waves (2/100 Hz), treatment duration was 30 minutes, once a day for ten consecutive days.43.47 ± 13.5742.23 ± 14.9815/1516/144.77 ± 1.765.10 ± 1.45VAS, the time to cessation of pustules, scabs, rash healing, the incidence of postherpetic neuralgia
Li et al. [22]20113127RT: Valaciclovir, 300 mg, orally twice daily for ten days; vitamin B1, 10 mg, orally three times daily for ten daysEA: EA on the ashi points + Jiaji (EX-B2); Zhigou (TE 6) + Houxi (SI 3); sparse and dense waves (2/100 Hz), treatment duration was 30 minutes, once a day for ten consecutive days.49.61 ± 16.3448.39 ± 17.0624/716/114.87 ± 2.255.25 ± 2.01VAS, the time to cessation of pustules, scabs, rash healing, and the incidence of postherpetic neuralgia
Lin [23]20152727RT: Indomethacin, 25 mg, three times daily for seven days; valaciclovir, 300 mg, orally twice daily for seven days; vitamin B1, 10 mg, orally three times daily for seven daysRT + EA: EA on the Hegu (LI4) + Waiguan (TE 5); Yanglingquan (GB34) + Zulinqi (GB41) + Taichong (LR3), continuous-wave (20 minutes for 80 Hz, 10 minutes for 20 Hz), treatment duration was 30 minutes, once a day for seven consecutive days.18–45: 7 persons; 46–60: 6 persons; 60–80: 14 persons18–45: 9 persons; 46–60: 8 persons; 60–80 : 10 persons13/1414/13Less than one weekLess than one weekVAS
Lu [24]20171213RT: Diclofenac, 75 mg, orally once daily for ten days; mecobalamin, 0.5 mg, orally three times daily for ten days; valaciclovir, 250 mg, orally three times for ten days; external 3% boric acid solutionRT + EA: EA on the Jiaji (EX-B2), continuous wave (60 Hz), treatment duration was 30 minutes, once a day for ten consecutive days.47.14 ± 10.3447.28 ± 10.415/76/7Not mentionedNot mentionedVAS, the time to cessation of pustules, scabs, and rash healing
Wei [25]20194545RT: Valaciclovir, 0.3 g, orally twice daily for 14 days; adenosylcobalamin, 0.5 mg, orally three times for 14 days; pregabalin, 150 mg, orally twice daily for 14 daysRT + EA: (EA on the Jiaji (EX-B2) + local points of rash, continuous-wave (2 Hz), treatment duration was 30 minutes, once a day for 14 consecutive days.56.53 ± 9.1557.89 ± 8.2222/2320/25Less than one weekLess than one weekVAS
Cheng [26]20182925RT: Valaciclovir, 0.3 g, orally twice daily for ten days; methylcobalamin, 0.5 mg, orally three times for ten days; If the pain were severe, oxycodone (10 mg) would be used.RT + EA: EA on the Jiaji (EX-B2) + local ashi points, continuous-wave (2 Hz), treatment duration was 30 minutes, once a day for ten consecutive days61.1 ± 2.1351.40 ± 3.1217/1212/134.72 ± 0.384 ± 0.36VAS, the incidence of postherpetic neuralgia

Abbreviations: C: control group; E: experimental group; VAS: visual analog scale.