Research Article

Traditional Chinese Medicine Is Associated with Reduced Risk of Readmission in Rheumatoid Arthritis Patients with Anemia: A Retrospective Cohort Study

Table 1

Comparison of demographic characteristics between RA patients with and without anemia.

CharacteristicBefore PSM matched valueAfter PSM matched value
Total (n = 811)RA with anemia (n = 471)RA without anemia (n = 340)Total (n = 656)RA with anemia (n = 328)RA without anemia (n = 328)

Age (years), n (%)
 20–60470 (57.95)261 (55.41)209 (61.47)0.09384 (58.54)185 (56.40)199 (60.67)0.27
 >60341 (42.05)210 (44.59)131 (38.53)272 (41.46)143 (43.60)129 (39.33)
 Median (IQR)56 (49, 66)56 (49, 67)56 (49, 65)0.2956 (49, 66)56 (48, 67)56 (49, 65)0.79

Gender, n (%)
 Female673 (82.98)392 (83.23)281 (82.65)0.83539 (82.16)270 (82.32)269 (82.01)0.92
 Male138 (17.02)79 (16.77)59 (17.35)117 (17.84)58 (17.68)59 (17.99)

Combined diseases, n (%)
 Hypertension176 (21.70)116 (24.63)60 (17.65)0.02129 (19.66)69 (21.04)60 (18.29)0.38
 Diabetes34 (4.19)21 (4.46)13 (3.82)0.6625 (3.81)13 (3.96)12 (3.66)0.84
 Hyperlipidemia91 (11.22)41 (8.70)50 (14.71)0.0176 (11.59)37 (11.28)39 (11.89)0.81

Basic medicine, n (%)
 DMARDs767 (94.57)448 (95.12)319 (93.82)0.42617 (94.05)309 (94.21)308 (93.90)0.87
 NSAIDs424 (52.28)253 (53.72)171 (50.29)0.34328 (50.00)158 (48.17)170 (51.83)0.35
 Glucocorticoids202 (24.91)118 (25.05)84 (24.71)0.91174 (26.52)90 (27.44)84 (25.61)0.60
 Folic acid241 (29.72)160 (33.97)81 (23.82)<0.01148 (22.56)67 (20.43)81 (24.70)0.19

End point events, n (%)
 Readmission107 (13.19)75 (15.92)32 (9.41)0.0187 (13.26)59 (17.99)28 (8.54)<0.01
 Interstitial lung disease94 (11.59)66 (14.01)28 (8.24)0.0178 (11.89)50 (15.24)28 (8.54)0.01
 Sjogren’s syndrome80 (10.11)55 (11.68)25 (7.35)0.0456 (8.54)32 (9.76)24 (7.32)0.26
 Surgical treatment60 (7.40)46 (9.77)14 (4.12)<0.0145 (6.86)31 (9.45)14 (4.27)0.01
 Death21 (2.59)15 (3.18)6 (1.76)0.2115 (2.29)9 (2.74)6 (1.83)0.43

Note. PSM: propensity score matching; DMARDs: disease-modifying antirheumatic drugs; NSAIDs: nonsteroidal anti-inflammatory drugs.