Comparative Pharmacokinetics of Seven Major Compounds in Normal and Atherosclerosis Mice after Oral Administration of Simiao Yong’an Decoction

Table 2

Liner range, regression equation, and correlation coefficient for seven compounds.

Compounds	Liner range (ng/ml)	Regression equation	Correlation coefficient (r^2)	LOD (ng/mL)	LLOQ (ng/mL)
Harpagide	2∼1500	y = 0.0021x − 0.0015	0.9982	1	2
Chlorogenic acid	1∼2000	y = 0.0020x + 0.0131	0.9978	0.5	1
Swertiamarin	5∼12000	y = 0.0040x − 0.0118	0.9980	2.5	5
Sweroside	5∼2500	y = 0.0056x + 0.0241	0.9969	2.5	5
Angoroside C	5∼500	y = 0.0027x − 0.0053	0.9981	2.5	5
Liquiritin	5∼500	y = 0.0150x + 0.0040	0.9998	2.5	5
Isoliquiritigenin	2∼500	y = 0.0297x − 0.0562	0.9968	1	2