Comparative Pharmacokinetics of Seven Major Compounds in Normal and Atherosclerosis Mice after Oral Administration of Simiao Yong’an Decoction

Table 3

Recovery and the matrix effect of seven target analytes in QC plasma samples (n = 5).

Compounds	QC conc. (ng/mL)	Recovery (%)		Matrix effect (%)
		Mean (%)	RSD (%)	Mean (%)	RSD (%)
Harpagide	600	101.14	6.37	95.40	3.74
	240	110.32	13.18	91.60	11.41
	38.4	96.61	7.33	96.65	3.13
Chlorogenic acid	800	104.87	5.66	112.72	10.05
	320	107.35	13.24	105.99	6.96
	51.2	100.99	5.50	95.46	4.97
Swertiamarin	4800	99.16	2.23	98.75	3.36
	1920	111.33	1.76	92.09	3.75
	307.2	92.68	9.61	92.37	6.59
Sweroside	1000	102.26	4.23	97.44	3.29
	400	109.48	6.11	89.23	2.33
	64	103.26	7.61	94.33	6.33
Angoroside C	200	98.04	4.06	106.36	6.23
	80	108.81	11.18	103.66	4.81
	12.8	90.17	12.76	109.11	11.46
Liquiritin	200	109.31	6.04	102.86	3.65
	80	106.23	6.80	100.54	3.08
	12.8	103.04	13.81	92.59	5.93
Isoliquiritigenin	200	92.80	8.01	108.26	2.50
	80	106.81	10.11	112.06	6.92
	12.8	94.89	7.79	110.64	11.11