Exploring the Effect and Mechanism of Si-Miao-Yong-An Decoction on Abdominal Aortic Aneurysm Based on Mice Experiment and Bioinformatics Analysis

Figure 3

Compounds-target network and Venn diagram of SMYAD-matched and AAA-related targets of SMYAD and AAA. (a) The network of 97 active compounds from SMYAD and 199 SMYAD-matched targets (sorted by nodes degree). The rose-red ellipse nodes represented target genes. The diamond nodes represented compounds (yellow for Flos Lonicerae, JYH for short; blue for Radix Scrophulariae, XS for short; purple for Radix Angelicae Sinensis, DG for short; green for Radix Glycyrrhizae, GC for short). C2, C4 were the common compounds of JYH and GC; C3 was the common compound of JYH, XS, DG, and GC; C5 was the common compound of JYH and XS. Among all active compounds, C2, C4 were the highest degree value nodes. (b) The Venn diagram of 199 SMYAD-matched and 1670 AAA-related targets.

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