Research Article
Vasorelaxant and Antihypertensive Effects of Bergenin on Isolated Rat Aorta and High Salt-Induced Hypertensive Rats
Table 1
Reveals the percent decrease in the BP and heart rate (HR) with different doses of bergenin in rats.
| Dose (mg/kg) | Normotensive rats | Hypertensive rats | BP (%) | HR (%) | BP (%) | HR (%) |
| Control | 99.9 ± 0.06 | 99.4 ± 0.04 | 99.2 ± 0.10 | 99.7 ± 0.07 | 0.003 | 7 ± 0.64 | 20 ± 1.23 | 10.50 ± 0.93 | 25 ± 1.02 | 0.03 | 24 ± 2.28 | 25 ± 1.84 | 31.50 ± 1.45 | 28 ± 3.04 | 0.3 | 42 ± 0.62 | 40 ± 1.03 | 48.75 ± 2.84 | 39 ± 2.04 | 3 | 58 ± 2.05 | 48 ± 2.30 | 68.75 ± 2.52 | 56 ± 3.14 |
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Values were tabulated as mean ± SEM for six experiments, where < 0.05, < 0.01 and < 0.001 vs. Control. |