Research Article

Vasorelaxant and Antihypertensive Effects of Bergenin on Isolated Rat Aorta and High Salt-Induced Hypertensive Rats

Table 1

Reveals the percent decrease in the BP and heart rate (HR) with different doses of bergenin in rats.

Dose (mg/kg)Normotensive ratsHypertensive rats
BP (%)HR (%)BP (%)HR (%)

Control99.9 ± 0.0699.4 ± 0.0499.2 ± 0.1099.7 ± 0.07
0.0037 ± 0.6420 ± 1.2310.50 ± 0.9325 ± 1.02
0.0324 ± 2.2825 ± 1.8431.50 ± 1.4528 ± 3.04
0.342 ± 0.6240 ± 1.0348.75 ± 2.8439 ± 2.04
358 ± 2.0548 ± 2.3068.75 ± 2.5256 ± 3.14

Values were tabulated as mean ± SEM for six experiments, where  < 0.05,  < 0.01 and  < 0.001 vs. Control.