Research Article

Molecular Mechanism of Crataegi Folium and Alisma Rhizoma in the Treatment of Dyslipidemia Based on Network Pharmacology and Molecular Docking

Table 3

Pathway and process of protein-protein interaction in the enrichment MCODE analysis.

MCODEGODescriptionLog 10 ()

MCODE1Hsa05200Pathways in cancer−30.6
Hsa05163Human cytomegalovirus infection−25.3
Hsa04933AGE-RAGE signaling pathway in diabetic complications−23.9
MCODE2Hsa05417Lipid and atherosclerosis−20.1
Hsa04657IL-17 signaling pathway−16.1
Hsa05200Pathways in cancer−13.7
MCODE3Hsa04080Neuroactive ligand-receptor interaction pathway−14.6
Go: 0007200Phospholipase C-activating G protein-coupled receptor signaling pathway−14.3
Go: 0007188Adenylate cyclase-modulating G protein-coupled receptor signaling pathway−13.9
MCODE4Hsa05200Pathways in cancer−9.7
Hsa05417Lipid and atherosclerosis−9.4
Hsa05208Chemical carcinogenesis—reactive oxygen species−9.4
MCODE5Hsa05204Chemical carcinogenesis—DNA adducts−10.6
Hsa00980Metabolism of xenobiotics by cytochrome P450−10.4
Go: 0006805Xenobiotic metabolic process−9.8
MCODE6Hsa04610Complement and coagulation cascades−7.7
Go: 0051897Positive regulation of protein kinase B signalling−7.2
Go: 0007596Blood coagulation−6.7