Research Article
Molecular Mechanism of Crataegi Folium and Alisma Rhizoma in the Treatment of Dyslipidemia Based on Network Pharmacology and Molecular Docking
Table 3
Pathway and process of protein-protein interaction in the enrichment MCODE analysis.
| MCODE | GO | Description | Log 10 () |
| MCODE1 | Hsa05200 | Pathways in cancer | −30.6 | Hsa05163 | Human cytomegalovirus infection | −25.3 | Hsa04933 | AGE-RAGE signaling pathway in diabetic complications | −23.9 | MCODE2 | Hsa05417 | Lipid and atherosclerosis | −20.1 | Hsa04657 | IL-17 signaling pathway | −16.1 | Hsa05200 | Pathways in cancer | −13.7 | MCODE3 | Hsa04080 | Neuroactive ligand-receptor interaction pathway | −14.6 | Go: 0007200 | Phospholipase C-activating G protein-coupled receptor signaling pathway | −14.3 | Go: 0007188 | Adenylate cyclase-modulating G protein-coupled receptor signaling pathway | −13.9 | MCODE4 | Hsa05200 | Pathways in cancer | −9.7 | Hsa05417 | Lipid and atherosclerosis | −9.4 | Hsa05208 | Chemical carcinogenesis—reactive oxygen species | −9.4 | MCODE5 | Hsa05204 | Chemical carcinogenesis—DNA adducts | −10.6 | Hsa00980 | Metabolism of xenobiotics by cytochrome P450 | −10.4 | Go: 0006805 | Xenobiotic metabolic process | −9.8 | MCODE6 | Hsa04610 | Complement and coagulation cascades | −7.7 | Go: 0051897 | Positive regulation of protein kinase B signalling | −7.2 | Go: 0007596 | Blood coagulation | −6.7 |
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