Transcriptomic Analysis Uncovers Immunogenic Characteristics of Ferroptosis for Myocardial Infarction and Potential Therapeutic Prediction of Chinese Herbs

Figure 1

Analysis of DEGs. (a) Percentage of cell types in the individual sample. GSM1561549, GSM1561550, GSM1561551 are the acute myocardial infarction group and GSM1561552, GSM1561553, GSM1561554 are the healthy group. The small rectangles of different colors in each bar represent one type of immune cell and the area represents the level of infiltration. (b) Heatmap of the culturing cells in different groups. The colors in the graph range from green to red, representing higher levels of infiltration, with each row representing one type of immune cell and each column representing one sample. The trial group (pink color) for patients with acute myocardial infarction including GSM1561549, GSM1561550, GSM1561551, while the contrast group (light blue color) for healthy people including GSM1561552, GSM1561553, GSM1561554. Red color indicates up-regulation and green color indicates downregulation. (c) Volcano plot of the DEGs between myocardial infarction group and normal control group. Genes with log2FC ≥ 1 and adj in red are marked as up-regulated genes and genes with −log2FC ≤ −1 and adj in blue are marked as downregulated genes.

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