Research Article
Synergistic and Attenuating Effect of Electroacupuncture on Aconitine in Improving Heart Failure and Its Calcium Regulation Mechanism
Table 2
The variation of proteins related to calcium regulation.
| Proteins | Roles played by the proteins | ACO versus HF | ACO + EA versus HF | ACO + EA versus ACO |
| SERCA2a | A key protein that regulates Ca2+ in cardiomyocytes | — | ↑ | ↑ | PLB | Inhibiting the affinity of SERCA2a to Ca2+ | ↓ | ↓ | ↓ | NCX1 | Exchanging Ca2+ inside and outside of myocardial cell membrane | — | ↓ | ↓ |
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↑, upregulated; ↓, downregulated; —, unchanged.
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