Research Article

Pimarane Diterpenoids from Aerial Parts of Lycopus lucidus and Their Antimicrobial Activity

Table 3

Results of the in vitro antibacterial activity (MIC) of compounds 10–14 against selected Gram-positive and Gram-negative bacteria.

MicroorganismsMinimum inhibitory concentration (µg/mL)
1011121314VanStrep

S. aureus (ATCC 9144)31.2531.2562.51251250.488
S. epidermidis (ATCC 12228)15.6231.251252502500.488
P. aeruginosa (ATCC 27853)62.562.51257.812
E. coli (ATCC 14948)1252507.812

Van: Vancomycin hydrochloride; Strep: streptomycin sulfate; negative control: 4% DMSO solution did not suppress the growth of the tested bacteria.