Actinidia deliciosa Mitigates Oxidative Stress and Changes in Pancreatic α-, β-, and δ-Cells and Immunohistochemical and Histological Architecture in Diabetic Rats
Table 3
Oxidative stress markers in the pancreatic homogenate of male rats in different groups.
Parameters
Control
ADAE
STZ
ADAE + STZ
TBARS (nmol/g tissue)
21.67 ± 0.78c
16.96 ± 0.63d
30.71 ± 1.08a
25.35 ± 0.78b
H2O2 (µmol/g tissue)
30.41 ± 0.98c
24.36 ± 0.72d
42.84 ± 1.63a
35.07 ± 1.27b
GSH (mmol/mg protein)
15.54 ± 0.61b
18.32 ± 0.64a
8.43 ± 0.24d
11.34 ± 0.38c
SOD (U/mg protein)
4.14 ± 0.149b
5.02 ± 0.184a
2.28 ± 0.075d
3.38 ± 0.111c
CAT (μmol/h/mg protein)
46 ± 1.65b
54 ± 1.03a
26 ± 0.86d
37 ± 1.08c
GST (µmol/hr/mg protein)
0.77 ± 0.028b
0.93 ± 0.034a
0.41 ± 0.016d
0.61 ± 0.022c
GPx (U/mg protein)
0.785 ± 0.034b
0.931 ± 0.031a
0.440 ± 0.010d
0.610 ± 0.030c
GR (U/mg protein)
0.876 ± 0.034b
1.033 ± 0.035a
0.531 ± 0.019d
0.722 ± 0.028c
Values are expressed as means ± SE (n = 6) for each treatment group. a, b, cMean values within a row not sharing a common superscript letter were significantly different, . Statistically significant variations are compared as follows: the ADAE and STZ groups compared with the control group and the ADAE + STZ group compared with the STZ group.