Research Article

Actinidia deliciosa Mitigates Oxidative Stress and Changes in Pancreatic α-, β-, and δ-Cells and Immunohistochemical and Histological Architecture in Diabetic Rats

Table 3

Oxidative stress markers in the pancreatic homogenate of male rats in different groups.

ParametersControlADAESTZADAE + STZ

TBARS (nmol/g tissue)21.67 ± 0.78c16.96 ± 0.63d30.71 ± 1.08a25.35 ± 0.78b
H2O2 (µmol/g tissue)30.41 ± 0.98c24.36 ± 0.72d42.84 ± 1.63a35.07 ± 1.27b
GSH (mmol/mg protein)15.54 ± 0.61b18.32 ± 0.64a8.43 ± 0.24d11.34 ± 0.38c
SOD (U/mg protein)4.14 ± 0.149b5.02 ± 0.184a2.28 ± 0.075d3.38 ± 0.111c
CAT (μmol/h/mg protein)46 ± 1.65b54 ± 1.03a26 ± 0.86d37 ± 1.08c
GST (µmol/hr/mg protein)0.77 ± 0.028b0.93 ± 0.034a0.41 ± 0.016d0.61 ± 0.022c
GPx (U/mg protein)0.785 ± 0.034b0.931 ± 0.031a0.440 ± 0.010d0.610 ± 0.030c
GR (U/mg protein)0.876 ± 0.034b1.033 ± 0.035a0.531 ± 0.019d0.722 ± 0.028c

Values are expressed as means ± SE (n = 6) for each treatment group. a, b, cMean values within a row not sharing a common superscript letter were significantly different, . Statistically significant variations are compared as follows: the ADAE and STZ groups compared with the control group and the ADAE + STZ group compared with the STZ group.