[Retracted] Meta-Analysis of the Efficacy and Safety of Chlorhexidine for Ventilator-Associated Pneumonia Prevention in Mechanically Ventilated Patients

Table 1

Basic information of the included study.

Study	Country	Departments	Frequency	Sample size, T/C	Intervention (solution and usage)		Outcomes
					T	C
Xia Shen, 2018	China	Respiratory medicine	Bid	37/37	0.12% chlorhexidine solution swab	Normal saline swab scrub	1
Bellissimo-rodrigues, 2009	Brazil	ICU	—	64/69	Rinse with 0.12% chlorhexidine solution	Rinse with placebo flushing	1, 2, 3, 4
Cabov, 2010	Croatia	ICU	Tid	17/23	0.2% chlorhexidine gel scrub	Placebo gel scrub	1, 4
Fourrie, 2005	France	ICU	Tid	114/114	0.2% gel wipe	Comfort gel wipe	1, 2
Huanhuan Wang, 2013	China	ICU	Tid	30/30	0.2% chlorhexidine solution rinse + scrub	Normal saline rinse + scrub	1
Jie Gao, 2019	China	ICU	Qid	45/45	0.12% chlorhexidine solution swab	Normal saline swab scrub	1
Koeman 2006	Netherlands	ICU	Qid	127/13	2% chlorhexidine gel scrub	Saline scrub	1
Meinberg, 2012	Brazil	CSICU	—	28/24	Brush with 0.2% chlorhexidine solution	Brush with placebo	1, 3, 4
Ming Liu, 2008	China	ICU	—	32/32	Rinse with 0.12% chlorhexidine solution	Rinse with placebo flushing	1
Scannapieco, 2009	USA	ICU	Bid	97/49	Brush with 0.2% chlorhexidine solution	Brush with placebo	1, 2, 3, 4
Tantipong, 2008	Thailand	ICU	Qid	58/52	Brush with 0.2% chlorhexidine solution	Brush with placebo	1, 2
Zoning Wei, 2014	China	ICU	Tid	108/110	Rinse with 0.12% chlorhexidine solution	Rinse with placebo flushing	1
Özçaka, 2012	Turkey	Respiratory ICU	Qid	29/32	0.12% chlorhexidine solution swab	Normal saline swab scrub	1, 2, 3, 4

T: chlorhexidine group; C: control group; ICU: intensive care unit; Bid: 2 times per day; Tid: 3 times a day; Qid: 4 times a day; Qd: once a day. 1: the incidence of VAP; 2: mortality; 3: days ventilated; 4: days in ICU.