Identification of Key Drug Targets and Molecular Mechanisms of Curcumae Rhizoma Acting on HBV-Related HCC: Weighted Correlation Network and Network Pharmacological Analyses

Table 2

Potential targets of active compounds of Curcumae Rhizoma in HBV-related HCC.

Gene symbol	Protein name	logFC	Degree	Bottleneck
TOP2A	DNA topoisomerase 2-alpha	3.261963	4	1
ESR1	Estrogen receptor	−2.27525	7	9
CDK1	Cyclin-dependent kinase 1	2.029494	4	1
CYP2C19	Cytochrome P450 2C19	−1.72843	1	1
PTGS2	Prostaglandin G/H synthase 2	−1.62628	3	2
SERPINE1	Plasminogen activator inhibitor 1	−1.55996	2	1
ADH1C	Alcohol dehydrogenase 1C	−1.4645	0	0
AURKA	Aurora kinase A	1.381586	3	1
HSD17B2	17-Beta-hydroxysteroid dehydrogenase type 2	−1.15057	1	1
LYZ	Lysozyme C	1.128273	0	0
PRKDC	DNA-dependent protein kinase catalytic subunit	1.029811	3	1