Research Article

Integrating Metabolomics and Network Pharmacology to Explore the Protective Effect of Ginsenoside Re against Radiotherapy Injury in Mice

Table 4

Metabolic pathways associated with potential biomarkers in serum.

Metabolic pathwayTotalExpectedHitsRaw pHolm adjustFDRImpact

Sphingolipid metabolism210.1830.000560.047260.02690.158
Linoleic acid metabolism50.0420.000640.053170.02691.0
Glycerophospholipid metabolism360.3030.002810.230150.07860.216
Fatty acid biosynthesis470.3930.006040.489250.12680.015
Biosynthesis of unsaturated fatty acids360.3020.034841.00.48780.0
Arachidonic acid metabolism360.3020.034841.00.48780.020
Alpha-linolenic acid metabolism130.1110.104091.01.00.0
Glycosylphosphatidylinositol (GPI)-anchor biosynthesis140.1210.111671.01.00.004
Glutathione metabolism280.2310.211731.01.00.027
Fatty acid elongation390.3310.282931.01.00.0
Fatty acid degradation390.3310.282931.01.00.0