Research Article

Integrating Metabolomics and Network Pharmacology to Explore the Protective Effect of Ginsenoside Re against Radiotherapy Injury in Mice

Table 5

Target information of G-Re in the treatment of IR in network pharmacology.

No.Gene symbolUniprot IDProtein name

1STAT3P40763Signal transducer and activator of transcription 3
2IL2P60568Interleukin-2
3AKT2P31751Serine/threonine-protein kinase AKT2
4ROCK1Q13464Rho-associated protein kinase 1
5AKT1P31749Serine/threonine-protein kinase AKT
6S1PR1P21453Sphingosine 1-phosphate receptor Edg-1
7IGF1RP08069Insulin-like growth factor I receptor
8EGFRP00533Epidermal growth factor receptor erbB1
9MMP1P03956Matrix metalloproteinase 1
10MAPK8P45983Mitogen-activated protein kinase 8
11MAPK9P45984Mitogen-activated protein kinase 9
12SYKP43405Tyrosine-protein kinase SYK
13GRB2P62993Growth factor receptor-bound protein 2
14MTORP42345Serine/threonine-protein kinase mTOR
15DPP4P27487Dipeptidyl peptidase IV
16SLC37A4O43826Glucose-6-phosphate translocase
17LTB4RQ15722Leukotriene B4 receptor 1
18PIK3CAP42336PI3-kinase p110-alpha subunit
19CSF1RP07333Macrophage colony stimulating factor receptor
20ADRB2P07550Adrenergic receptor beta
21NTRK1P04629Nerve growth factor receptor Trk-A
22NTRK2Q16620Neurotrophic tyrosine kinase receptor type 2
23ROCK2O75116Rho-associated protein kinase 2
24HDAC6Q9UBN7Histone deacetylase 6
25MMP9P14780Matrix metalloproteinase 9
26MMP2P08253Matrix metalloproteinase 2
27CDK2P24941Cyclin-dependent kinase 2
28SELLP14151Leukocyte adhesion molecule-1
29SELPP16109P-selectin
30SRCP12931Src tyrosine kinase
31GSRP00390Glutathione reductase
32SOD2P04179Superoxide dismutase
33PPP5CP53041Serine/threonine-protein phosphatase 5
34PLA2G2AP14555Phospholipase A2