Clerodendrum wallichii Merr Methanol Extract Protected Alcohol-Induced Liver Injury in Sprague-Dawley Rats by Modulating Antioxidant Enzymes

Table 1

Effect of methanol extract of Clerodendrum wallichii (MECW) on the percentage change of body and liver weights in alcohol-treated SD rats.

Treatment group	Dose	Change of body weight (%)	Change of liver weight (%)
Nonalcoholic control	None	4.46 ± 0.242	3.04 ± 0.176
Alcoholic control	(ethanol 1 mL/100 g b.w. of rats)	16.92 ± 0.846^a	5.55 ± 0.311^a
C. wallichii + ethanol	200 mg/kg	13.44 ± 0.297^a^b	4.57 ± 0.154^a
C. wallichii + ethanol	400 mg/kg	12.26 ± 0.653^a^b	3.71 ± 0.159^b
C. wallichii + ethanol	600 mg/kg	8.42 ± 0.658^a^b	3.15 ± 0.062^b
C. wallichii + ethanol	800 mg/kg	4.76 ± 0.372^b	3.06 ± 0.128^b
C. wallichii + ethanol	1000 mg/kg	7.28 ± 0.365^a^b	3.16 ± 0.104^b
Silymarin + ethanol	(25 mg/kg)	3.54 ± 0.290^b	2.99 ± 0.095^b

Values are expressed as means ± SEM of five rats in each group. ^aData differed significantly when compared to the nonalcoholic control group within the respective column. ^bData differed significantly when compared to the alcoholic control group within the respective column.