Gallic Acid Inhibits Mesaconitine-Activated TRPV1-Channel-Induced Cardiotoxicity

Figure 3

Effect of GA and the coadministrative of MA on the mean fluorescence intensity of nucleus and ROS in H9c2 cells. (a) Effects of GA (25, 50, and 100 µM) or pretreatment with BCTC (10 µM) on the increase of the mean fluorescence intensity of the nucleus in H9c2 cells induced by 250 µM MA. (b) Effects of GA (25, 50, and 100 µM) or pretreatment with BCTC (10 µM) on the increase of the mean fluorescence intensity of ROS in H9c2 cells induced by 250 µM MA. Data are presented as the mean ± SD (n = 3).  < 0.01 versus control group and ^## < 0.01 versus MA group.

(a)

(b)