Inhibition of α-Amylase, α-Glucosidase, and Lipase, Intestinal Glucose Absorption, and Antidiabetic Properties by Extracts of Erodium guttatum

Table 4

Effects of E. guttatum extracts on body weight in mice made diabetic by HFD-STZ.

Body weight (g)
	Initial weight	Final weight
Control normal	25.11 ± 4.18	29.53 ± 1.02
Diabetic control (STZ-HFD)	35.23 ± 1.87	36.08 ± 3.18†††
Diabetic + metformin (300 mg/kg)	33.3 ± 2.07ns	32.21 ± 0.7###ns
Diabetic + EGA (200 mg/kg)	35.12 ± 1.49ns	34.3 ± 1.11†ns
Diabetic + EGM (200 mg/kg)	34.61 ± 2.07ns	34.21 ± 1.04†ns
Diabetic + EGE (200 mg/kg)	34.75 ± 1.83ns	33.32 ± 1.2#

The values are the mean ± SEM (n = 6). , , , and compared to the normal control group. # and ### compared to the diabetic control group (HFD-STZ). † and ††† compared to the diabetic + metformin. Ns = not significant to the diabetic + metformin or diabetic control group (HFD-STZ). EGA: aqueous extract of E. guttatum; EGM: methanolic extract of E. guttatum; EGE: ethanolic extract of E. guttatum.