Research Article
[Retracted] Antihypertensive and Vasorelaxant Effects of Citrus aurantifolia Linn. Fruit: Proposed Mechanisms
Table 1
Acute hypotensive effect of the aqueous methanol extract of Citrus aurantifolia fruit.
| Parameters | 0.25 g/kg | 0.50 g/kg | 0.75 g/kg |
| SBP (mmHg) | 0 h | 124.13 ± 0.44 | 123.88 ± 0.55 | 123.63 ± 0.56 | 2 h | 120.25 ± 0.59 | 113.63 ± 1.59 | 95.75 ± 1.61 | 4 h | 123.75 ± 0.49 | 118.00 ± 1.49 | 103.8 ± 3.20 | 6 h | 123.38 ± 0.53 | 122.63 ± 0.38 | 122.75 ± 0.49 |
| DBP (mmHg) | 0 h | 92.68 ± 0.48 | 92.62 ± 0.39 | 93.54 ± 0.32 | 2 h | 67.45 ± 3.79 | 67.69 ± 3.04 | 62.81 ± 1.61 | 4 h | 79.13 ± 3.29 | 72.13 ± 1.95 | 74.25 ± 2.11 | 6 h | 93.56 ± 0.23 | 93.96 ± 0.24 | 94.57 ± 0.30 |
| MAP (mmHg) | 0 h | 103.16 ± 0.25 | 103.04 ± 0.25 | 103.56 ± 0.18 | 2 h | 85.69 ± 2.72 | 79.75 ± 1.75 | 76.38 ± 0.89 | 4 h | 94.00 ± 2.28 | 87.00 ± 1.16 | 84.13 ± 1.13 | 6 h | 103.50 ± 0.16 | 103.58 ± 0.14 | 103.96 ± 0.22 |
| HR (beats/min) | 0 h | 382.10 ± 0.50 | 382.66 ± 0.31 | 382.6 ± 0.45 | 2 h | 381.75 ± 1.13 | 375.88 ± 1.44 | 368.3 ± 1.89 | 4 h | 383.50 ± 1.18 | 374.50 ± 0.91 | 373.6 ± 0.98 | 6 h | 382.06 ± 0.71 | 383.58 ± 0.14 | 381.3 ± 0.67 |
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Values are presented in mean ± SEM. and in comparison to control (0 h). |