In Vivo Efficacy, Toxicity Assessment, and Elemental Analysis of Traditionally Used Polyherbal Recipe for Diarrhea

Table 2

Effect of polyherbal recipe extracts on castor oil-induced diarrhea.

Groups	Onset of diarrhea (min)	No. of diarrheal feces	Inhibition of diarrhea %	Total no. of feces	Inhibition of defecation %	Total weight of feces	Rats with diarrhea	% rats protected
Control (normal saline + co)	69.66 ± 7.23	8.66 ± 0.57	—	8.66 ± 0.57	—	1.63 ± 0.15	3	0
Loperamide 5 mg/kg + co	211 ± 4.58	0.66 ± 0.57	92.37	4.99 ± 2.07	42.37	0.70 ± 0.1	1	66.66
Recipe 100 mg/kg + co	196.66 ± 75.05	0.66 ± 0.57	92.37	1.99 ± 0.63	77.02	1.16 ± 0.85	1	66.66
Recipe 200 mg/kg + co	240 ± 0	0	100	0.66 ± 0.51	92.37	0.26 ± 0.25	0	100
Recipe 400 mg/kg + co	240 ± 0	0	100	0	100	0	0	100

Values taken as mean ± SEM (n = 3), one-way ANOVA.  = ,  = , and ns = nonsignificant versus control.