Research Article
In Vivo Efficacy, Toxicity Assessment, and Elemental Analysis of Traditionally Used Polyherbal Recipe for Diarrhea
Table 5
Physical patterns of albino rats in polyherbal crude extract-treated (400 mg/kg) and control groups.
| Parameters | Observations | 30 minutes | 4 h | 24 h | 48 h | 7 days | 14 days | CG | PG | CG | PG | CG | PG | CG | PG | CG | PG | CG | PG |
| Skin appearance | √ | √ | √ | √ | √ | √ | √ | √ | √ | √ | √ | √ | Eyes | √ | √ | √ | √ | √ | √ | √ | √ | √ | √ | √ | √ | Mucous membrane | √ | √ | √ | √ | √ | √ | √ | √ | √ | √ | √ | √ | Respiratory system | √ | √ | √ | √ | √ | √ | √ | √ | √ | √ | √ | √ | CNS | √ | √ | √ | √ | √ | √ | √ | √ | √ | √ | √ | √ | Somatomotor activity | √ | √ | √ | √ | √ | √ | √ | √ | √ | √ | √ | √ | Behavioral pattern | √ | √ | √ | √ | √ | √ | √ | √ | √ | √ | √ | √ | Sleep | √ | √ | √ | √ | √ | √ | √ | √ | √ | √ | √ | √ | Coma and convulsion | Nf | Nf | Nf | Nf | Nf | Nf | Nf | Nf | Nf | Nf | Nf | Nf | Salivation | √ | √ | √ | √ | √ | √ | √ | √ | √ | √ | √ | √ | Lethargy | Nf | Nf | Nf | Nf | Nf | Nf | Nf | Nf | Nf | Nf | Nf | Nf | Urination (color) | √ | √ | √ | √ | √ | √ | √ | √ | √ | √ | √ | √ | Itching | Nf | Nf | Nf | Nf | Nf | Nf | Nf | Nf | Nf | Nf | Nf | Nf | Feces consistency | √ | √ | √ | √ | √ | √ | √ | √ | √ | √ | √ | √ | Mortality | Nf | Nf | Nf | Nf | Nf | Nf | Nf | Nf | Nf | Nf | Nf | Nf |
|
|
CG = vehicle control group, PG = polyherbal extract-treated group, √ = normal and good, and Nf = not found.
|