Research Article
Analyzing the Therapeutic Mechanism of Mongolian Medicine Zhonglun-5 in Rheumatoid Arthritis Using a Bagging Algorithm with Serum Metabonomics
Table 2
Potential biomarkers between the control group and model group.
| | tR (min) | Measured mass | 106 mass deviation | Chemical formula | Compound | Metabolic pathway |
| | 4.195 | 370.2345 | 2.7 | C20H34O6 | Prostaglandin G1 | Arachidonic acid metabolism | | 8.131 | 392.2191 | 2.0 | C22H32O6 | 10-hydroperoxy-H4-neuroprostane | Arachidonic acid metabolism | | 8.619 | 1092.7293 | 0.8 | C56H104N2O18 | Ganglioside GA2 (d18 : 1/18 : 0) | Glycosphingolipid biosynthesis | | 4.445 | 1541.9183 | 0.1 | C75H135N3O29 | Ganglioside GD3 (d18 : 1/23 : 0) | Glycosphingolipid biosynthesis | | 3.936 | 1382.8229 | 4.1 | C68H122N2O26 | Ganglioside GM2 (d18 : 0/18 : 1 (11Z)) | Glycosphingolipid biosynthesis | | 0.097 | 254.2237 | 3.5 | C16H30O2 | Palmitoleic acid | Fatty acid metabolism | | 7.648 | 302.2244 | 0.7 | C20H30O2 | Eicosapentaenoic acid | Fatty acid metabolism | | 4.827 | 278.2246 | 0 | C18H30O2 | α-Linolenic acid | Fatty acid metabolism | | 3.487 | 284.2707 | 2.8 | C18H36O2 | Stearic acid | Fatty acid metabolism | | 6.150 | 283.2873 | 0.7 | C18H37NO | Octadecanamide | Fatty acid metabolism | | 9.832 | 308.2701 | 4.5 | C20H36O2 | Eicosadienoic acid | Fatty acid metabolism | | 9.705 | 193.0739 | 0 | C10H11NO3 | Phenylacetylglycine | Amino acid metabolism | | 7.561 | 117.0792 | 1.7 | C5H11NO2 | L-valine | Amino acid metabolism | | 4.974 | 285.2302 | 0.7 | C16H31NO3 | Myristoylglycine | Amino acid metabolism | | 4.149 | 243.1833 | 0.4 | C13H25NO3 | N-undecanoylglycine | Amino acid metabolism | | 9.801 | 115.0637 | 3.5 | C5H9NO2 | L-proline | Amino acid metabolism | | 6.923 | 499.2961 | 1.4 | C26H45NO6S | Tauroursodeoxycholic acid | Bile acid metabolism | | 6.700 | 111.0435 | 1.8 | C3H5N3O | Gytosine | Pyrimidine metabolism | | 0.480 | 446.3386 | 2.2 | C28H46O4 | 13′-Carboxy-γ-tocopherol | Vitamin E metabolism | | 5.517 | 424.3330 | 2.6 | C29H44O2 | α-Tocotrienol | Vitamin E metabolism | | 4.396 | 301.2979 | 0.7 | C18H39NO2 | Sphinganine | Sphingolipid signaling metabolism | | 4.826 | 807.5771 | 0.8 | C46H82NO8P | PC (22 : 5 (7Z, 10Z, 13Z, 16Z, 19Z)/16 : 0) | Phospholipid metabolism | | 4.397 | 539.5281 | 0.7 | C34H69NO3 | Cer (d18 : 0/16 : 0) | Sphingolipid metabolism | | 4.597 | 317.2926 | 1.3 | C18H39NO3 | Phytosphingosine | Sphingolipid metabolism |
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