|
| Include studies | Years (Y) | Total sample/N | Treatment strategy | Course of treatment/Weeks | Adverse reactions |
| Treatment group (male/female) | Control group (male/female) | Treatment group | Control group |
|
| Li and Jia [8] | 2009 | 52 (20/32) | 50 (20/30) | Shugan Ningxin Decoction (1 dose/d, decoct 300 ml of decoction with water and take it twice warmly in the morning and evening) | Sertraline hydrochloride tablets (oral, 50 mg/once per night) | 2/8 | Yes (none in the treatment group; 7 cases in the control group) |
| Jiang and Zhou [9] | 2015 | 30 (16/14) | 25 (13/12) | Chaihu guizhi keel oyster Decoction (1 dose/d, add 1.5 g cinnabar to take, take it twice in the morning and evening, decoct twice and combine to obtain 400 ml decoction) | Betaloc (oral, 25 mg/time, once daily) | 2/4 | None |
| Yao [10] | 2016 | 32 (9/23) | 28 (10/18) | On the basis of the control group, jieyu decoction was added | Sertraline hydrochloride (50 mg, once/day) + lorazepam tablets (1.0 mg, 3 times/day) + psychotherapy | 2/2 | None |
| Liu [11] | 2016 | 30 (7/23) | 30 (5/25) | Yangxin dingji Decoction (1 dose/d, decoct 300 ml of decoction with water and take it twice warmly in the morning and evening) | Oryzanol tablets (oral, 3 times/d, 20 mg each time) | 1/4 | Yes (none in the treatment group; 2 cases in the control group) |
| Leng [12] | 2018 | 36 (14/22) | 36 (15/21) | Yangxin chaihuan Decoction (Oral, powder, 50–100 ml each time, twice/d) | Patients with high heart rate: Betaloc (oral, 47.5 mg/tablet, 1/d); Patients with insomnia: Right zopiclone tablets (oral, 3 mg/tablet/time) | Unknown/4 | None |
| Ma [13] | 2020 | 30 (10/20) | 30 (9/21) | Jiawei erxian decoction (decocting, taking 1 packet each time, 2 packets/day) | Flupentixol and melitracen tablets (oral, 2 tablets/day) | 1/4 | Yes (none in the treatment group; 5 cases in the control group) |
| Wang [14] | 2020 | 33 (17/16) | 33 (18/15) | Shengxian Decoction (Granules, brewing 300 ml with warm water, oral, 2/d, 150 ml/time) | Oryzanol tablets (oral, 3 times/d, 20 mg/2 tablets each time) | 1/4 | None |
| Dai et al. [15] | 2021 | 30 (9/21) | 30 (10/20) | On the basis of the control group, Tianwang Buxin Decoction was added (one dose of 250 ml per day, taken in the morning and evening) | Oryzanol tablets (oral, 3 times/d, 20 mg/2 tablets each time) | 1/4 | None |
| Tong et al. [16] | 2021 | 43 (16/27) | 43 (18/25) | On the basis of the control group, Suanzaogen Decoction was added (decoction, 1 dose per day, taken in the morning and evening) | Oryzanol tablets (oral, 3 times/d, 20 mg/2 tablets each time) + vitamin B1 (oral, 10 mg each time, 3 times/d) | 1/4 | None |
| Zhang [17] | 2021 | 33 (13/20) | 32 (13/19) | On the basis of the control group, huanglian zhengdan decoction was added (decoction pieces of traditional Chinese medicine, each dose of decoction 300 ml, 150 ml/time, oral, 2/d) | Oryzanol tablets (oral, 3 times/d, 20 mg each time) + vitamin B1 (oral, 10 mg each time, 3 times/d) [patients with high heart rate: Betaloc (oral, 23.75–47.5 mg); in case of insomnia, right zopiclone tablets (oral, 2 mg)] | 1/4 | None |
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