Effect of Traditional Chinese Medicine on Treating Antibiotic-Associated Diarrhea in Children: A Systematic Review and Meta-Analysis

Table 3

Effect of TCM combined with conventional therapy on other indices.

Outcome or Subgroup	Studies	Participants	Effect Estimate(Mean Difference, 95% CI)	Heterogeneity
Frequency of diarrhea on the third day after TCM intervention	5	509	−1.18 [−1.77, −0.58]	96%
The change of CD3+	2	205	6.40 [−8.77, 21.57]	0%
Time for bowel sounds to return to normal	2	204	−6.65 [−17.27, 3.96]	97%
The change of CD4+	3	281	5.99 [−2.42, 14.41]	0%
The change of CD8+			−1.86 [−7.90, 4.18]	0%
The change of CD4 : CD8			0.19 [−0.12, 0.49]	0%
Effect of vomiting improvement time	3	346	−1.14 [−1.64, −0.64]	86%
The change of diamine oxidase	2	241	−3.69 [−6.45, −0.92]	0%
IgA	2	196	0.56 [0.02, 1.10]	0%
IgG	2	196	3.49 [0.69, 6.29]	0%
IgM	2	196	0.38 [−0.07, 0.83]	0%
Average hospital stay	3	299	−1.31 [−2.11, −0.51]	88%
Hs-CRP	2	226	−0.28 [−0.89, 0.34]	0%
IL-8			−1.16 [−2.07, −0.26]	0%
TNF			−0.83 [−1.12, −0.54]	0%