XueFu ZhuYu Decoction Alleviates Cardiopulmonary Bypass-Induced NLRP3 Inflammasome-Dependent Pyroptosis by Inhibiting IkB-<i>α</i>/NF-<i>κ</i>B Pathway in Acute Lung Injury Rats

<div>XFZYD attenuated pulmonary vascular leakage and inflammatory cell infiltration levels in rat models with CPB-induced ALI. (a) Protein, (b) the number of total cells, and (c) neutrophils in bronchoalveolar lavage fluid (BALF) at 8 h after the CPB operation were measured to estimate pulmonary vascular leakage. (d) Immunohistochemistry was employed to estimate the average intensity of myeloperoxidase (MPO) in lung tissues of rats with CPB-induced acute lung injury. Scare bar = 100 <i>μ</i>m. 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Evidence-Based Complementary and Alternative Medicine

fig3

Figure 3

Figure 3: XueFu ZhuYu Decoction Alleviates Cardiopulmonary Bypass-Induced NLRP3 Inflammasome-Dependent Pyroptosis by Inhibiting IkB-<i>α</i>/NF-<i>κ</i>B Pathway in Acute Lung Injury Rats 

Figure 3 | XueFu ZhuYu Decoction Alleviates Cardiopulmonary Bypass-Induced NLRP3 Inflammasome-Dependent Pyroptosis by Inhibiting IkB-α/NF-κB Pathway in Acute Lung Injury Rats 