Methyl Gallate Suppresses Tumor Development by Increasing Activation of Caspase3 and Disrupting Tumor Angiogenesis in Melanoma

Figure 5

MG delays metastasis to the lymph node. (a) Fluorescent images showing lymph nodes of PBS- or MG-treated mice. Scale bar 250 μm. (b) Magnification images showing the cytokeratin and LYVE-1 expression in lymph nodes of PBS- or MG-treated mice. (c and d) Quantification of the fluorescence intensity of cytokeratin in the cortex (c) and medulla (d). Quantification of the fluorescence intensity of LYVE-1 in the cortex (e) medulla (f). MG, methyl gallate. Values represent mean ± SD. ; ; versus control.

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