Review Article

Effects of Acupuncture on Neuropathic Pain Induced by Spinal Cord Injury: A Systematic Review and Meta-Analysis

Table 1

Characteristics of the included studies.

StudyPublicationyearCountrySampleInterventionAge (years)Sex (M/F)Onset of SCIASIA gradeInjured spinal segmentsAcupunctureprotocolOutcome measure
CECECECECE

Zheng et al. [25]2021China3535Rehabilitative + drugRehabilitative + drug + acupuncture36.35 ± 10.8238.48 ± 11.4018/1720/15(5.08 ± 0.84) (m)(4.64 ± 0.68) (m)Not mentionedCervical, thoracic, and lumbar regionElectroacupuncture (2 Hz) at “Jiaji” (EX-B2) + scalp acupuncture at the motor, sensory, spiritual, and emotional areas of Jiao’s; the treatment duration was 30 minutes, once a day for 28 consecutive daysVAS
Cheng [26]2018China2727DrugDrug + acupuncture47.98 ± 5.2748. 16 ± 5.1218/917/10(4.91 ± 1.05) (m)(5.11 ± 0.87) (m)Not mentionedCervical, thoracic, and lumbar regionElectroacupuncture (sparse and dense waves) at “Jiaji” (EX-B2); the treatment duration was 30 minutes, once a day for 25 consecutive daysVAS, PRI, PPI
Chen et al. [27]2014China1818DrugAcupuncture18–6220/16With a minimum of 2 months and a maximum of 50 yearsABCDCervical, thoracic, and lumbar regionElectroacupuncture (sparse and dense waves) at “Governor Vessel” acupoints; the treatment duration was 30 minutes, once a day for 30 consecutive daysVAS, PRI, PPI
Chen et al. [28]2015China2323Rehabilitative + drugRehabilitative + drug + acupuncture38.2 ± 9.620/26(2.5 ± 0.8) (m)Not MentionedNot mentionedAcupuncture at Baihui (GV 20), He-Gu (LI4), and Ashi points, 6 times a week for 4 weeksVAS, PRI, PPI
Fang et al. [29]2016China3030Drug + massageDrug + massage + acupuncture38.2 ± 6.144/16(3.8 ± 0.4) (m)Not mentionedNot mentionedElectroacupuncture at “Jiaji” (EX-B2); the treatment duration was 30 minutes, once a day for 20–30 days based on clinical needVAS, PPI
Irene et al. [30]2017USA812Rehabilitative + drugRehabilitative + drug + acupuncture46.141.16/210/213 years7.6 yearsABCDNot mentionedAuricular acupuncture at the anterior cingulate, thalamus, omega-2, Shen Men, point zero; the treatment duration was 3-7 days, once a week for 8 weeksNRS

m, months; C, control group; E, experimental group; VAS, visual analogue scale; NRS, numeric rating scale; PPI, present pain intensity; PRI, pain region index.