Research Article
Identification and Comparison of Potential Biomarkers by Proteomic Analysis in Traditional Chinese Medicine-Based Heart Failure Syndromes
Table 1
Clinical data of participants.
| | | Yang deficiency (n = 12) | Qi-yin deficiency (n = 12) | Control (n = 12) | value |
| | Gender (female/male) | 5/7 | 7/5 | 6/6 | >0.05 | | Age (Mean ± SD) | 59−85 (71.75 ± 7.45) | 54−85 (76.58 ± 9.91) | 55−80 (67.75 ± 7.18) | >0.05 | | Hemoglobin g/L (Mean ± SD) | 60−144 (108.25 ± 26.13) | 108−146 (127.83 ± 10.60) | 116−154 (136.09 ± 10.33) | 0.002 | | Blood platelet 10^9/L (Mean ± SD) | 104−325 (169.5 ± 65.37) | 111−246 (174.58 ± 38.59) | 123−331 (228.09 ± 68.28) | 0.043 | | Alanine transaminase IU/L (Mean ± SD) | 3.9–66.5 (23.31 ± 16.38) | 6.2–46.5 (27.77 ± 12.57) | 9.1–62.9 (26.71 ± 17.99) | 0.078 | | Aspartate transaminase IU/L (Mean ± SD) | 17.4–58.2 (35.17 ± 12.90) | 17.7–56.4 (36.76 ± 10.26) | 17.1–46.1 (29.77 ± 8.52) | 0.284 | | Creatinine μmol/L (Mean ± SD) | 81–379.5 (192.82 ± 88.04) | 50.6–105.6 (80.36 ± 16.84) | 50–98.9 (67.2 ± 14.79) | <0.001 | | Na + mEq/L (Mean ± SD) | 134–141.5 (136.86 ± 4.03) | 131.5–141.2 (138.76 ± 3.29) | 139.9–143 (141.25 ± 1.85) | 0.006 | | Ka + mmol/L (Mean ± SD) | 3.31–6.41 (4.38 ± 0.84) | 3.26–4.88 (3.96 ± 0.44) | 3.32–4.75 (4.15 ± 0.40) | 0.254 | | CRP mg/L (Mean ± SD) | 0.8–117.3 (25.44 ± 33.11) | 3–50.44 (13.33 ± 17.55) | 1–7.28 (2.92 ± 1.79) | 0.139 | | BNP pg/mL (Mean ± SD) | 686−31049 (13893 ± 11542) | 136–28049 (7487 ± 10221) | 21–102 (35.44 ± 32.37) | 0.008 |
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