Modified Yuejuwan Inhibited Cholesterol Accumulation and Inflammation in THP-1 Macrophage-Derived Foam Cells by Inhibiting the Activity of the TRIM37/TRAF2/NF-κB Pathway

Figure 1

OxLDL induced the formation of human THP-1 macrophage foam cells. (a) Oil Red O staining indicating that oxLDL uptake upregulated in foam cells. Magnification: 200x. (b). The contents of TC, FC, and CE increased in foam cells. vs. THP-1. (c) qRT-PCR used to examine the relative mRNA levels of TRIM8, TRIM13, TRIM14, TRIM22, TRIM37, and TRIM39 in THP-1 and foam cells, respectively. vs. THP-1, vs. THP-1, vs. THP-1. (d) The translocation of NF-κB promoted in foam cells. vs. THP-1.

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