Research Article
[Retracted] Analysis of the Efficacy of Multidrug Combination Chemotherapy Regimens for Osteosarcoma and the Management of Chemotherapeutic Reactions
Table 3
Chemotherapy reactions during chemotherapy in 21 patients with osteosarcoma (n, %).
| | Chemotherapy reactions | Grade | | I | II | III | IV | Total |
| | Hematotoxicity | | | | | | | Leukopenia | 1 (4.76) | 5 (23.81) | 9 (42.86) | 6 (28.57) | 21 (100.00) | | Decreased haemoglobin | 2 (9.52) | 4 (19.05) | 11 (52.38) | 4 (19.05) | 21 (100.00) | | Decreased platelets | 1 (4.76) | 1 (4.76) | 5 (23.81) | 7 (33.33) | 14 (66.66) | | Gastrointestinal reactions | | | | | | | Nausea, vomiting | 6 (28.57) | 9 (42.86) | 3 (14.29) | 3 (14.29) | 21 (100.00) | | Oral mucositis | 6 (28.57) | 3 (14.29) | 4 (19.05) | 1 (4.76) | 14 (66.67) | | Gastrointestinal bleeding | 3 (14.29) | 1 (4.76) | 1 (4.76) | 0 (0.00) | 5 (23.81) | | Diarrhoea | 1 (4.76) | 1 (4.76) | 0 (0.00) | 0 (0.00) | 2 (9.52) | | Hepatotoxicity | | | | | | | Elevated alanine transaminase | 6 (28.57) | 8 (38.10) | 0 (0.00) | 0 (0.00) | 14 (66.67) | | Cardiotoxicity | | | | | | | Cardiac damage | 6 (28.57) | 3 (14.29) | 2 (9.52) | 0 (0.00) | 11 (52.38) | | Nephrotoxicity | | | | | | | Haematuria, proteinuria | 4 (19.05) | 1 (4.76) | 0 (0.00) | 0 (0.00) | 5 (23.81) | | Skin toxicity | | | | | | | Rash | 4 (19.05) | 2 (9.52) | 0 (0.00) | 0 (0.00) | 6 (28.57) | | Pigmentation | 2 (9.52) | 1 (4.76) | 0 (0.00) | 0 (0.00) | 3 (14.29) |
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