Integrated UPLC-Q-TOF-MS/MS and Network Pharmacology Approach to Investigating the Metabolic Profile of Marein of <i>Coreopsis tinctoria</i> Nutt.

<table class="table-group" id="tab4"><tr><td><table class="table"><tr><td class="thead-hr" colspan="3"><hr/></td></tr><tr class="thead"><td class="align_left">Parameter</td><td class="align_center">Unit</td><td class="align_center">SD rat</td></tr><tr><td class="thead-hr" colspan="3"><hr/></td></tr><tr><td class="align_left">t<sub>1/2</sub></td><td class="align_center">min</td><td class="align_center">177.6923</td></tr><tr><td class="align_left">CL<sub>int</sub></td><td class="align_center">mL·(min·mg protein)<sup>−1</sup></td><td class="align_center">0.0065</td></tr><tr><td class="align_left">CL′<sub>int</sub></td><td class="align_center">mL·(min·kg)<sup>−1</sup></td><td class="align_center">11.7000</td></tr><tr><td class="align_left">CL<sub>H</sub></td><td class="align_center">mL·(min·kg)<sup>−1</sup></td><td class="align_center">9.9382</td></tr><tr><td class="align_left">ER</td><td class="align_center">—</td><td class="align_center">0.1506</td></tr><tr class="table-tr"><td colspan="3"><hr class="tbody-hr"/></td></tr></table></td></tr></table>

<div>The results of the half-time period, CL<sub>int</sub>, CL′<sub>int</sub>, and CL<sub>H</sub> of marein in rats liver microsomes.</div>

Evidence-Based Complementary and Alternative Medicine

tab4

Table 4

Table 4: Integrated UPLC-Q-TOF-MS/MS and Network Pharmacology Approach to Investigating the Metabolic Profile of Marein of <i>Coreopsis tinctoria</i> Nutt. 

Evidence-Based Complementary and Alternative Medicine

Integrated UPLC-Q-TOF-MS/MS and Network Pharmacology Approach to Investigating the Metabolic Profile of Marein of Coreopsis tinctoria Nutt.

Table 4