Early Stage Finding of an Immune-Enhanced Genetic Subtype of Nonsmall Cell Lung Cancer Related with T-Cell Depletion

Figure 8

There are three distinct immune subgroups, each of which reacts differently to immunotherapy and chemotherapy. The GSE93157 and RNAseq dataset was analyzed for a submap (a), and the GSE93157 and GSE cohort was analyzed for a submap (b). (c) Estimated concentrations of IC50 for cisplatin, paclitaxel, sorafenib, erlotinib, and crizotinib found in the RNAseq dataset. IC50 values estimated for cisplatin, paclitaxel, sorafenib, erlotinib, and crizotinib in the GSE cohort. Ns indicates that there was no statistical significance. less than 0.01, less than 0.001, and less than 0.0001.

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