Research Article

Globularia alypum Extracts Attenuate Hyperglycemia and Protect against Various Organ Toxicities in Alloxan-Induced Experimental Diabetic Rats

Table 2

Average body weight (g), food intake (g/rat), and water in GAWE and GAME type 1 diabetes treated rats. In diabetic rats, a decrease in body weight and an increase in water and food consumption were observed.

Body weightFood consumption (g/rat/day)Water consumption (ml/rat/day)
W1W2W3W1W2W3W1W2W3

Nondiabetic (NC)181 ± 11197 ± 13221 ± 1319.71 ± 318.73 ± 520.13 ± 518.719.319.73
Diabetic (D)169 ± 9157 ± 10143 ± 1126 ± 531 ± 1135 ± 541 ± 347 ± 248 ± 7
D + GAWE175 ± 7183 ± 9209 ± 823.1 ± 322.1 ± 420.7 ± 725 ± 524 ± 323 ± 3
D + GAME171 ± 9180.7 ± 7197.1 ± 627.1 ± 725.9 ± 324.6 ± 429.1 ± 727.3 ± 625 ± 4
D + GB175 ± 7181 ± 3203 ± 525.1 ± 524.1 ± 722.3 ± 527 ± 325 ± 424 ± 2

In GAME- or GAWE-treated diabetic rats, a minor decrease in body weight was observed; however, food and water consumption increased.