Globularia alypum Extracts Attenuate Hyperglycemia and Protect against Various Organ Toxicities in Alloxan-Induced Experimental Diabetic Rats
Table 2
Average body weight (g), food intake (g/rat), and water in GAWE and GAME type 1 diabetes treated rats. In diabetic rats, a decrease in body weight and an increase in water and food consumption were observed.
Body weight
Food consumption (g/rat/day)
Water consumption (ml/rat/day)
W1
W2
W3
W1
W2
W3
W1
W2
W3
Nondiabetic (NC)
181 ± 11
197 ± 13
221 ± 13
19.71 ± 3
18.73 ± 5
20.13 ± 5
18.7
19.3
19.73
Diabetic (D)
169 ± 9
157 ± 10
143 ± 11
26 ± 5
31 ± 11
35 ± 5
41 ± 3
47 ± 2
48 ± 7
D + GAWE
175 ± 7
183 ± 9
209 ± 8
23.1 ± 3
22.1 ± 4
20.7 ± 7
25 ± 5
24 ± 3
23 ± 3
D + GAME
171 ± 9
180.7 ± 7
197.1 ± 6
27.1 ± 7
25.9 ± 3
24.6 ± 4
29.1 ± 7
27.3 ± 6
25 ± 4
D + GB
175 ± 7
181 ± 3
203 ± 5
25.1 ± 5
24.1 ± 7
22.3 ± 5
27 ± 3
25 ± 4
24 ± 2
In GAME- or GAWE-treated diabetic rats, a minor decrease in body weight was observed; however, food and water consumption increased.